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A prospective, multicenter, randomized controlled study of unicompartmental knee arthroplasty for the treatment of severe knee joint degeneration

A prospective, multicenter, randomized controlled study of unicompartmental knee arthroplasty for the treatment of severe knee joint degeneration

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100999
Enrollment
Unknown
Registered
2025-04-17
Start date
2023-12-01
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ingle compartment degeneration of the knee joint under special circumstances such as anterior cruciate ligament injury, patellofemoral joint degeneration, knee joint flexion contracture above 15 degrees, knee joint inversion above 15 degrees, etc

Interventions

Unilateral knee arthroplasty (UKA) group:Knee unicompartmental replacement (UKA)
Total knee arthroplasty (TKA) group:Total Knee Replacement (TKA)

Sponsors

Qingdao Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age must be >= 50 years old; 2.Diagnosed knee joint degeneration with unilateral knee joint pain; 3.Knee joint degeneration degree exceeds III degree; 4.Primary knee joint degeneration,Prior to participating in the study, I had a thorough understanding of the study and had sufficient informed consent ability; 5.I voluntarily signed an informed consent form and was able to treat according to the expected treatment procedure and complete all follow-up visits;

Exclusion criteria

Exclusion criteria: 1. Patients with cardiopulmonary insufficiency who cannot tolerate surgery; 2.Patients with rheumatism and pathological knee joint degeneration; 3. Patients with incomplete coagulation function that affects surgery; 4. Patients with combined effects of other diseases on pain or functional impairment assessment; 5. Patients with infectious diseases (which may affect the surgical effect) ; 6. Patients who have undergone knee joint surgery such as meniscus in the past; 7. Patients diagnosed with >= 2 knee joint compartment pain; 8. Patients who have participated in clinical trials of other drugs or medical devices before screening but have not yet been included in the group; 9. The researchers believe that patients who are not suitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
VAS score;

Secondary

MeasureTime frame
LYSHOLM Scale;IKDC score;Degree of knee joint inversion and eversion, deformity, and osteophyte in the knee joint;

Countries

China

Contacts

Public ContactTengbo Yu

Qingdao Municipal Hospital

ytb8912@163.com+86 532 82912261

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026