Obstructive Sleep Apnea-Hypopnea Syndrome
Conditions
Interventions
Sugammadex group (Group S):After the operation, the infusion of general anesthetics was stopped, and when T2 of TOF reappeared, group S was injected Sugammadex with 5ml of (2mg/kg) saline diluent wit
Neostigmine Formation (Group N):After surgery, the infusion of general anesthetics was stopped, and when T2 of TOF reappeared, group N was injected 5ml of neosmin (0.02mg/kg) and atropine (0.01mg/kg)
Sponsors
The Second Norman Bethune Hospital of Jilin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.All enrolled patients underwent UPPP surgery, and the preoperative examination and evaluation met the indications. 2.Patients and their families should give informed consent to the study, sign informed consent forms, and the medical ethics Committee should approve the study. 3.No contraindications to anesthesia, no serious cardiopulmonary and other important organ dysfunction or serious systemic diseases. 4.American Society of Anesthesiologists grade I to II.
Exclusion criteria
Exclusion criteria: 1.Patients with mental disorders, psychological disorders or loss of consciousness. 2.Patients with surgical contraindications. 3.Intolerance or history of allergy to narcotic drugs. 4.Patients with diseases of the blood system or immune system. 5.Patients with myasthenia gravis. 6.Patients with abnormal heart, liver and kidney function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The 24-h postoperative Quality of Recovery-15 (QoR-15) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuromuscular recovery time (time to recovery of a train-of-four (TOF) ratio =0.9);Extubation time ;Diaphragmatic excursion ;:Postoperative complications ;Intraoperative outcomes ;Post-anesthesia care unit (PACU) outcomes; | — |
Countries
China
Contacts
Public ContactZhao Peng
The Second Norman Bethune Hospital of Jilin University
Outcome results
None listed