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Effects of Intrathecal Hydromorphone on Postoperative Analgesia Duration and Efficacy in Patients Undergoing Anorectal Surgery: A Randomized, Double-Blind, Controlled Trial

Effects of Intrathecal Hydromorphone on Postoperative Analgesia Duration and Efficacy in Patients Undergoing Anorectal Surgery: A Randomized, Double-Blind, Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100994
Enrollment
Unknown
Registered
2025-04-17
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorectal diseases

Interventions

Hydromorphone combined with ropivacaine intrathecal anesthesia group (H group):Intrathecal injection of hydromorphone combined with ropivacaine
Ropivacaine intrathecal anesthesia group (C group):Intrathecal injection of ropivacaine

Sponsors

Deyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with benign anorectal diseases (haemorrhoids, anal fissure, anal fistula, perianal abscess, acromegaly, etc.) who are scheduled to undergo surgical treatment; 2. Age 18 years or older; 3. ASA classification I-III.

Exclusion criteria

Exclusion criteria: 1. Allergy or intolerance to the study drug; 2.History of chronic pain or prolonged preoperative use of analgesics; 3. Coagulation disorders and administration of anticoagulant drugs; 4. History of spinal trauma or surgery; 5. Incomplete conversion of intrathecal anaesthesia to general anaesthesia. 5. Refusal of the patient to co-operate and early withdrawal.

Design outcomes

Primary

MeasureTime frame
Duration of postoperative analgesia;Pain score;

Secondary

MeasureTime frame
Adverse reactions (including sedation level and degree of nausea and itching);Consumption of opioids;Patient satisfaction;

Countries

China

Contacts

Public ContactZhang Xianjie

Deyang People's Hospital

16177211@qq.com+86 139 8108 8319

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026