Sedation before MRI examination
Conditions
Interventions
Test group:Subjects were sedated using dexmedetomidine nasal spray combined with midazolam oral solution
Control group:Subjects were sedated using dexmedetomidine hydrochloride nasal drops combined with midazolam oral solution
Sponsors
Children's Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 2 Years
Inclusion criteria
Inclusion criteria: 1. ASA I-II level; 2. Age 1-2 years old; 3. Children weighing 10-15kg 4. requiring sedation before MRI examination
Exclusion criteria
Exclusion criteria: 1. ASAIII level and above; 2. nasal mucosa injury in children; 3. severe upper respiratory tract infection; 4. dysfunction of liver and kidney; 5. History of sedative drug allergy; 6. Experienced general anesthesia within 2 weeks; 7.Use of sedative hypnotics (including benzodiazepines such as diazepam and barbiturates such as phenobarbital, etc.) within 1 week; 8. mental system diseases and cognitive dysfunction; 9. Arrhythmia, especially chronic arrhythmia; 10. Severe obesity (weight =50% above the standard body weight); 11. follow-up missing; 12. Refuse to participate in this study; 13. Other conditions that the investigator determines are not suitable for participation in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation onset time;sedation recovery time;overall sedation time; adverse event;Sedation satisfaction rate;Success rate of rescue sedation;vital signs; | — |
Countries
China
Contacts
Public ContactJinjin Huang
Children's Hospital, Zhejiang University, School of Medicine
Outcome results
None listed