None listed
Conditions
Interventions
Experimental group (Group E):Esketamine 0.2 mg/kg plus 2.5mg/kg propofol
Control group (Group C):Fentanyl 1 µg/kg plus 2.5mg/kg propofol
Sponsors
Diqingzhou Tibetan Hospital of Yunnan Province
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-65 years, ASA I-II, living in high-altitude areas (>= 3000 meters above sea level) for more than 1 year, who plan to undergo gastroscopy, Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiovascular and pulmonary diseases, pulmonary hypertension, sleep apnea syndrome, or COPD; 2. Patients with recent acute respiratory infections; 3. BMI > 30kg/?; 4. Patients anticipated to have difficult airways; 5. Patients with uncontrolled hypertension (systolic pressure >= 160 mmHg); 6. Patients with significant liver and kidney function abnormalities; 7. Patients who may be allergic to the medications used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of low blood pressure;Aldrete score;Incidence of body movements;Operator satisfaction;Incidence of low heart rate;Total dose of propofol;Airway intervention event; | — |
Countries
China
Contacts
Public ContactXue Hui
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine; Diqing Tibetan Hospital, Yunnan Province
Outcome results
None listed