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Clinical observation of the effect of bupivacaine liposome on postoperative inflammatory factor levels and lung function in elderly patients undergoing thoracoscopic surgery

Clinical observation of the effect of bupivacaine liposome on postoperative inflammatory factor levels and lung function in elderly patients undergoing thoracoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100946
Enrollment
Unknown
Registered
2025-04-17
Start date
2024-03-11
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Bupivacaine liposomal group :Using the random number table method, the patients in this group underwent ultrasound-guided erector spinae plane block on the affected side after anesthesia, and the lipo
Ropivacaine group:Using the random number table method, the patients in this group underwent ultrasound-guided erector spinae plane block on the affected side after anesthesia, and ropivacaine 100mg w

Sponsors

Gezhouba Central Hospital of Sinopharm
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.ASAI.~III.; 2.Patients over 65 years of age who are scheduled for elective thoracoscopic lobe wedge resection under bronchial intubation general anesthesia, all of whom are informed and have signed a consent form.

Exclusion criteria

Exclusion criteria: 1.Previous history of thoracic surgery; 2.Previous history of COPD, pulmonary function tests FEV/FVC 37kg; 4.Received radiotherapy and chemotherapy before surgery; 5.Patients with abnormal coagulation function; 6.Patients with psychiatric disorders who are unable to cooperate; 7.Patients with an infection of the skin at the puncture site.

Design outcomes

Primary

MeasureTime frame
Interleukin-6;Interleukin-8;

Secondary

MeasureTime frame
Diffusion index;Oxygenation index;Pain scores;Incidence of nausea and vomiting;Number of cases of salvage analgesia;Occurrence of puncture point infection;Lung-related complications;

Countries

China

Contacts

Public ContactZhan Weiwei

Gezhouba Central Hospital of Sinopharm

504661407@qq.com+86 136 1717 8509

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026