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Clinical Study on the Safety and Efficacy of ultrasound Therapy Combined with Replasty Series Products on the Skin

Clinical Study on the Safety and Efficacy of ultrasound Therapy Combined with Replasty Series Products on the Skin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100937
Enrollment
Unknown
Registered
2025-04-17
Start date
2025-04-20
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wrinkles, destruction of barrier after aesthetic medicine

Interventions

Test group:Ultrasound therapy and treatment using test products
Control group:Ultrasound therapy and treatment using control products

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Healthy Asian women; 2. Age> 45 years old; 3. Sagging of the lower part of the face on both sides (scored by the Skin Aging Atlas >=2); 4. Lack of firmness on both sides of the face (10-level score>=3 points and =2); 6. Ptosis of the upper and outer eyelids on both sides (scored by the Skin Aging Atlas >=2); 7. Obvious nasolabial folds on both sides (scored by the Skin Aging Atlas >=2); 8. Plan to undergo facial ultrasound treatment; 9. Understand the purpose and process of the research, and be able to understand it; 10. Willing and able to complete the entire pilot study and follow-up schedule; 11. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnant or intending to become pregnant or not taking effective contraceptive measures during the study; 2. Any cutaneous or systemic disease (acute and/or chronic) (hyperthyroidism, psoriasis, eczema, acne, diabetes mellitus, severe heart, liver and kidney disease, coagulation dysfunction) and/or any local or systemic treatment that, in the opinion of the investigators, may interfere with the measured parameters; 3. Received any cosmetic, dermatological or surgical procedure (hyperthermia, chemical peel, filler, injection, lift, etc.) in the study area that may interfere with the study, or arranged such treatment during the study; 4. Have a history of allergy to the ingredients of the tested products; 5. Participate in another clinical trial or volunteers are in the exclusion stage of the trial, so they are unable to participate in the trial; 6. Those who cannot be contacted by telephone; 7. There are implants under the skin, such as metal, plastic, silicone and other implants, which may interfere with the therapeutic effect of Ultherapy.

Design outcomes

Primary

MeasureTime frame
Lower sagging;crow's feet;Skin firmness;Upper and outer eyelid ptosis;Security assessment;nasolabial folds;

Secondary

MeasureTime frame
Skin stratum corneum moisture content;Skin roughness;

Countries

China

Contacts

Public ContactLi Li

West China Hospital, Sichuan University

hxskincosm@qq.com+86 28 8542 2075

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026