Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients who were clinically diagnosed with knee osteoarthritis met the diagnostic criteria of the Osteoarthritis Diagnosis and Treatment Guideline (2018 edition). (2) patients with mild to moderate pain symptoms requiring drug control; (3) age of 18-75 years old, both sexes; (4) no serious heart, brain, liver, kidney, lung and other important organ diseases; (5) no history of allergy to topical plaster; (6) Have not participated in other drug clinical trials in the past 6 months; (7) agree to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) severe pain requiring combination of two analgesics; (2) using analgesics within two weeks; (3) painful joint swelling or fever; (4) skin ulceration or infection at the pain site; (5) patients who were allergic to any component of the study medication and could not adhere to it; (6) patients with bone and joint dislocation, tumor, tuberculosis and other causes of neck, back and leg pain; (7) pregnant and lactating women; (8) abnormal liver and kidney function; (9) those who could not express their chief complaints correctly and could not cooperate in the study, such as patients with mental illness or severe neurosis; (10) unable to follow up regularly or cooperate with the investigators; (11) other patients considered by the investigator to be unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| knee joint function;pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of knee joint function and pain;safety evaluation; | — |
Countries
China
Contacts
Mianzhu Hospital, West China Hospital, Sichuan University