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Nalbuphine Combined with Stellate Ganglion Block for Postoperative Analgesic Effect and Gastrointestinal Function Recovery in Gynecological Laparoscopic Surgery: A Clinical Study

Nalbuphine Combined with Stellate Ganglion Block for Postoperative Analgesic Effect and Gastrointestinal Function Recovery in Gynecological Laparoscopic Surgery: A Clinical Study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100898
Enrollment
Unknown
Registered
2025-04-16
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteromyoma

Interventions

Nalbuphine Group (N):After ultrasound-guided stellate ganglion block, the patient was prepared with naborphine 1.0mg / kg 10min before the end of surgery, with a load of 4ml, background amount of 4ml
Sufentanil (S):After ultrasound-guided stellate ganglion block, the patient prepared an intravenous analgesia pump with sufentanil 1.0 ug / kg, 10min before the end of the operation, with a load of 4

Sponsors

The Eighth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 Patients aged 18-60 years 2 or their legally authorized persons agree to participate in this study 3 ASA grade I~ III 4 body mass index (BMI) 18-29.5 kg / m^2

Exclusion criteria

Exclusion criteria: 1 Surgical history of gastrointestinal disease 2 huge uterine or pelvic severe adhesions 3 bradycardia (HR <50 bpm / min), hypotension (SBP <90mmHg) 4 patients with severe mental disorders and language disorders patients 5 and related drug allergy 6 have chronic pain disease or long-term application of analgesic drugs 7 pregnant or lactation women 8 monoamine oxidase inhibitors within two weeks

Design outcomes

Primary

MeasureTime frame
Resting and activity status NRS scores at each postoperative point; Ramsay scores at each postoperative point;

Secondary

MeasureTime frame
Analgesic dosage;Number of effective and ineffective presses of the analgesic pump;

Countries

China

Contacts

Public ContactPeng Yue

The Eighth Affiliated Hospital of Sun Yat-sen University

hg_84396959@sina.com+86 159 8668 6015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026