The primary diseases were liver tumor, alcoholic cirrhosis, hepatitis cirrhosis, chronic acute liver failure, hepatolenticular degeneration, autoimmune hepatitis, Booga syndrome, etc
Conditions
Interventions
Gold Standard:The immune status and rejection reaction were determined according to biochemical indexes of liver function and pathological diagnosis of liver biopsy.
Index test:General information, biochemical data (leukocyte, AST, ALT, PT) and imaging/pathological data. Peripheral blood is going to be collected to be analyzed for chimera, immune cells, and immune
Sponsors
Second Xiangya Hospital of CSU
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.The primary diseases were liver tumor, alcoholic cirrhosis, hepatitis cirrhosis, chronic acute liver failure, hepatolenticular degeneration, autoimmune hepatitis, Booga syndrome, etc;
Exclusion criteria
Exclusion criteria: 1.Symptoms of infection appeared before surgery; 2.There were serious complications of heart, brain, lung and kidney before operation; 3.Vaccination history within one month prior to surgery; 4.He had a history of PD-L1, PD-1 and other immunotherapy within one month before surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutamic-pyruvic transaminase, ALT;Liver biopsy;Glutamic oxalacetic transaminase, AST;Total bilirubin, TBIL;Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immune cells;Immune molecule; | — |
Countries
China
Contacts
Public ContactYaxun Huang
Second Xiangya Hospital of CSU
Outcome results
None listed