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Clinical effect of oxeridine combined with remazolam and propofol in elderly patients with ERCP

Clinical effect of oxeridine combined with remazolam and propofol in elderly patients with ERCP

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100840
Enrollment
Unknown
Registered
2025-04-16
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Oxelidine + propofol group (Group P):Propofol was given 2mg/kg for anesthesia induction, and propofol was maintained 2-8mg/kg/h
Oxellidine + Remazolam group (Group R):Remazolam was given 0.2mg/kg for anesthesia induction, and remazolam was maintained under anesthesia at 0.5-2mg/kg/h
Oxelidine + propofol + remazolam group (P+R group):Remazolam 0.1mg/kg and propofol 1mg/kg were given for anesthesia induction, and propofol 2 to 4mg/kg/h and remazolam 2 to 1mg/kg/h were maintained un

Sponsors

Hebei Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: Elective ERCP, age >=65 years old, ASA grade I-III.

Exclusion criteria

Exclusion criteria: (1) Acute or severe cardiac insufficiency; (2) There were significant abnormalities in preoperative lung function (COPD acute attack, asthma acute stage, SPO2<=90% of preoperative breathing air, etc.); (3) Patients with severe cerebrovascular diseases and cognitive deficits; (4) Emergency ERCP surgery.

Design outcomes

Primary

MeasureTime frame
The incidence of hypoxemia;The incidence of hypotension;

Secondary

MeasureTime frame
Recovery time;The incidence of nausea and vomiting;Incidence of body movement and coughing;VAS pain score;Surgeon satisfaction;

Countries

China

Contacts

Public ContactWu Yajing

Hebei Provincial People's Hospital

843001577@qq.com+86 180 3182 5359

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026