Dry Eye
Conditions
Interventions
Treatment group for 2 weeks:Continuous stimulation was performed for 2 weeks with an autologous lacrimal gland secretagogue
Treatment group for 4 weeks:Continuous stimulation was performed for 4 weeks with an autologous lacrimal gland secretagogue.
Sponsors
The Second Affiliated Hospital of Zhejiang University, School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Schirmer test (surface anesthesia) in at least one eye between 2 and 5 mm / 5 min; 2. Voluntarily participate in the experiment, sign the informed consent, and be willing to cooperate with the tests and questionnaires included in the experiment; 3. Aged 18 years and above.
Exclusion criteria
Exclusion criteria: 1. lactating or pregnant women; 2. Patients with serious systemic or immune diseases; 3. Had undergone eye surgery, including eyelid surgery, LASIK surgery, cataract surgery, etc., within 6 months before enrollment; 4. Wear contact lenses within the last 30 days; 5. Have had more serious eye discomfort symptoms in the last 7 days; 6. Eyelid inflammation, paralysis, ectropion and other eyelid diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear secretion;MG expressibility score;Meibum quality score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ocular surface disease index;Standard Patient Evaluation Score of Eye Dryness;Non-invasive tear film rupture time;Non invasive tear river height;Bulbar Redness ;Tear film break-up time;Corneal fluorescent staining score; | — |
Countries
China
Contacts
Public ContactJin Xiuming
The Second Affiliated Hospital of Zhejiang University, School of Medicine
Outcome results
None listed