Diabetic erectile dysfunction
Conditions
Interventions
Treatment group:In combination with conventional therapy, patients received orally administered Yanghuo Huoxue Decoction modified based on syndrome differentiation. Administration protocol: 200 mL per
Control group:In combination with conventional therapy, patients received oral tadalafil (5 mg per dose) administered every other day at approximately 15:00 hours, with a total treatment course of 12
Sponsors
Shenzhen Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: (1) Those who meet the Western medical diagnostic criteria for diabetes mellitus and erectile dysfunction, and the ED diagnosis is after DM; (2) Blood glucose has been controlled at a good level, FPG<=7.0mmol/L, postprandial 2hPG<=10.0mmol/L, glycosylated hemoglobin <=7.0%; (3) Those who meet the TCM diagnostic criteria for diabetic erectile dysfunction (kidney deficiency and blood stasis syndrome); (4) Men < 20 years old < 60 years old with normal libido; (5) Those who voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with type 1 diabetes or type 2 diabetes who have no sexual life; (2) Patients with severe cardiovascular disease, cerebrovascular disease, liver and kidney insufficiency, hematopoietic system disease, and neuropathy; (3) Combined with urethritis, acute prostatitis, urinary stones and other diseases; (4) History of pelvic surgery or within 6 months; (5) Those who take diuretics, antihypertensive drugs, sedatives, antidepressants, hormones and related drugs for a long time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of the 5-item International Index of Erectile Function (IIEF-5) questionnaire;Quality of Erection Questionnaire (QEQ) score;Erectile Hardness Score (EHS);Chinese Medical Syndrome Scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum homocysteine (HCY) ;Fasting plasma glucose (FPG);2-hour postprandial glucose (2hPG);Glycated hemoglobin (HbA1c);Prostacyclin (PGI2);Endothelin(ET);Serum nitric oxide (NO) levels;Total Antioxidant Capacity (T-AOC);lutathione Peroxidase (GSH-Px);Total Cholesterol (TC);Triglyceride (TG); | — |
Countries
China
Contacts
Public ContactHong Zhiming
Shenzhen Traditional Chinese Medicine Hospital
Outcome results
None listed