None listed
Conditions
Interventions
Liposomal bupIvacaine paravertebral blockade group:After the induction of general anaesthesia, preoperative paravertebral nerve block was performed under the lateral position of the patient, and the d
and the paravertebral nerve block was performed under the direct vision of thoracoscopy before the end of the operation. According to the surgical site, four points of T4-7 were selected for paraverte
Ropivacane paravertebral blockade group:After the induction of general anaesthesia, preoperative paravertebral nerve block was performed under the lateral position of the patient, and the drug was 0.5
and paravertebral nerve block was performed under the direct vision of thoracoscopy before the end of the operation. Four points of T4-7 were selected for paravertebral nerve block, and the drug was 0
Sponsors
Shanghai Chest Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Understand in detail the nature, significance, possible benefits, possible inconvenience and potential risks of the trial before the trial. Be able to understand the procedures and methods of the study, be willing to strictly comply with the clinical trial protocol to complete the trial, and voluntarily sign the written informed consent; 2. subjects undergoing elective open/thoracoscopic lung surgery in lateral position under general anaesthesia; 3. >=18 years of age, regardless of gender; 4. 18 kg/m^2 <= BMI <= 30 kg/m^2; 5. American Society of Anaesthesiologists (ASA) classification ? ~ ?.
Exclusion criteria
Exclusion criteria: 1. subjects with a history of myocardial infarction or unstable angina within 6 months prior to randomisation, or a history of severe arrhythmia such as atrioventricular block of degree II or greater, or NYHA cardiac function class II or greater; 2. subjects with comorbid psychiatric disorders (e.g., schizophrenia, depression, etc.) and cognitive dysfunction; 3. patients with comorbid sensory disorders such as pain hypersensitivity; 4. patients with comorbid other chronic somatic pain that may interfere with postoperative pain assessment; 5. patients with previous thoracic surgery; 6. anticipated severe thoracic adhesions on the operative side, etc; 7. allergy to bupivacaine or ropivacaine; 8. patients who need to return to ICU with an endotracheal tube for postoperative support and cannot be extubated early; 9. patients with hearing, vision or comprehension impairment who are unable to complete the scale evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric Rating Pain Score;Morphine equivalence for opioid use; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15;overall benefit of analgesia score;postoperative nausea and vomiting;Incidence of postoperative eruptive pain;The 12-items Short Form Health Survey; | — |
Countries
China
Contacts
Public ContactYuwei Qiu
Shang Hai Chest Hospital
Outcome results
None listed