Skip to content

To study brain network changes in migraine patients based on EEG and fMRI

To study brain network changes in migraine patients based on EEG and fMRI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100796
Enrollment
Unknown
Registered
2025-04-15
Start date
2022-09-03
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Interventions

Healthy control group:None

Sponsors

People's Hospital of Jianyang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Case group: 1.Age: 18-60 years old; 2.Meet the above diagnostic criteria, have or have no precursor symptoms (flashing light, dark spots, paresthesia, etc.) and are in the interattack period (no attack within 24 hours before and after the examination); 3.No previous neurological diseases such as epilepsy, cerebral infarction, cerebral hemorrhage, brain trauma, etc.; 4.No history of mental illness; 5.Right-handed; 6.Agree to participate in the study and sign the informed consent. Healthy controls: 1. Age: 18-60 years old; 2. No previous history of nervous system related diseases (epilepsy, headache, dizziness, cerebral infarction, cerebral hemorrhage, brain tumor, etc.) and signs; 3. No history of head trauma and surgery; 4. No history of mental illness; 5. No history of migraine in the first or second degree relatives of the family; 6. No contraindications to EEG and MRI examination; 7. Be right-handed.

Exclusion criteria

Exclusion criteria: 1.Age 60 years old; 2.Secondary headache and other types of primary headache caused by cerebral hemorrhage, intracranial aneurysm, intracranial tumor, intracranial arteriovenous malformation, cerebral infarction, etc. 3), combined with heart dysfunction, liver and kidney failure, chronic obstructive pulmonary disease and autoimmune diseases; 3.There are mental disorders and neurological diseases; 4.Alcohol or drug abusers; 5.Patients with contraindications for fMRI scanning, such as metal dentures, pacemakers, artificial metal heart valves, etc., or those who cannot cooperate to complete the examination.

Design outcomes

Primary

MeasureTime frame
Brain network connection;Microstate;Source location;ALFF?ReHo;

Secondary

MeasureTime frame
Pain disability;

Countries

China

Contacts

Public ContactYan Zhou

Jianyang City People's Hospital

514803043@qq.com+86 28 27237850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026