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The impact of low triiodothyronine syndrome on the prognosis of patients with septic shock

The impact of low triiodothyronine syndrome on the prognosis of patients with septic shock

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100780
Enrollment
Unknown
Registered
2025-04-15
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious shock combined with low T3 syndrome

Interventions

Sponsors

Huai'an First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1: Age 18 or above 2: Diagnostic criteria for sepsis determined by sepsis 3.0 3: No previous thyroid disease 4: The serum thyroid hormone level after admission meets the diagnostic criteria for low T3

Exclusion criteria

Exclusion criteria: 1: Primary thyroid disease 2: Autoimmune Disease 3: Tumor 4: Pregnancy 5: Recent medications taken, such as amiodarone, carbamazepine, lithium, phenytoin, heparin, interferon, and interleukin, or chemotherapy that may affect thyroid metabolism

Design outcomes

Primary

MeasureTime frame
28 day all-cause mortality rate;

Secondary

MeasureTime frame
The maximum dose of norepinephrine used within 24 days after admission to the ICU;SOFA score, APACHEII score;Within 24 hours after enrollment, blood routine, biochemistry BNPPCT Troponin index;ICU stay time or total length of hospital stay;Initial Lac value and lactate values at 3, 6, and 24 hours after enrollment;Ventilation machine usage and offline time;

Countries

China

Contacts

Public ContactPeng Zhang

Huai'an First People's Hospital

zhangpenghayy@163.com+86 158 0523 6181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026