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Development and Validation of a Predictive Model for Acute Ischemic Stroke Based on a Novel Carotid Plaque Ultrasound Scoring System and Clinical Data

Development and Validation of a Predictive Model for Acute Ischemic Stroke Based on a Novel Carotid Plaque Ultrasound Scoring System and Clinical Data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100777
Enrollment
Unknown
Registered
2025-04-15
Start date
2025-05-15
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

Gold Standard:Refer to the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2023 for the diagnostic criteria:(1) sudden onset
(2) focal neurological deficits, with a few cases presenting global neurological impairment
(3) presence of a responsible lesion on imaging or symptoms/signs persisting for more than 24 hours
(4) exclusion of non-vascular causes
and (5) exclusion of cerebral hemorrhage via CT/MR
Index test:1) General information
2) Laboratory indicators
3) Conventional ultrasound characteristics of carotid plaques
4) Carotid plaque ultrasound angiography score.

Sponsors

Hebei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Presence of carotid atherosclerosis characteristics; 2.Availability of complete ultrasound and clinical data; 3.Carotid plaque contrast-enhanced ultrasound (CEUS) results available; 4.Brain CT/MRI imaging performed within the past two weeks;

Exclusion criteria

Exclusion criteria: 1.History of stroke; 2.Previous carotid stent implantation or carotid endarterectomy; 3.Carotid stenosis due to other causes, such as Takayasu arteritis or fibromuscular dysplasia; 4.Carotid plaque presenting as hyperechoic with acoustic shadowing, obscuring lumen assessment; 5.Presence of malignant tumors, severe dysfunction of the liver, kidney, heart, or lungs, or serious infections;

Design outcomes

Primary

MeasureTime frame
Carotid plaque ultrasound angiography score;Conventional ultrasound characteristics of carotid plaques;

Secondary

MeasureTime frame
General information;Laboratory indicators;

Countries

China

Contacts

Public ContactHuimin Niu

Hebei General Hospital

33788170@qq.com+86 311 8598 9973

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026