Female Androgenetic Alopecia
Conditions
Interventions
Concentrated growth factor combined with 2% minoxidil group:2% minoxidil was applied to the whole scalp area, and one scalp was injected with concentrated growth factor locally
microneedle combined with 2% minoxidil group:2% minoxidil was applied to the whole scalp area, and one scalp was combined with electric micro-needle for local acupuncture.
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 18 to 60; 2. androgenic alopecia was diagnosed clinically, and the type of female alopecia was Ludwig I-III; 3. Stable vital signs; 4. Subjects are required to sign an informed consent form for voluntary participation; 5. During the experiment, do not perm or dye your hair and keep the same hairstyle.
Exclusion criteria
Exclusion criteria: 1. Hair loss caused by other reasons, including but not limited to plum toxic hair loss, cicatricial hair loss, resting hair loss, etc. 2. Patients with scalp infection, ulceration or other skin diseases such as psoriasis; 3. people who dye their hair and perm; 4. allergic to minoxidil, medical iodophor, lidocaine and other drugs; 5. those with infectious diseases such as hepatitis B, tuberculosis, syphilis and AIDS; 6. Patients with anemia, hypertension, coronary heart disease, diabetes, brain diseases, connective tissue diseases, severe endocrine diseases, hemorrhagic diseases and thrombocytopenia-related diseases; 7. those with definite heart, liver and kidney function damage and low immune function; 8. People with neuropsychiatric diseases; 9. Systematically used glucocorticoids or immunosuppressants in the last 4 weeks; 10. Those who have received platelet concentrate, microneedle therapy, oral and topical drugs related to alopecia treatment in the past 3 months; 11. people with scar constitution; 12. pregnant and lactating women; 13. Those who can't receive regular treatment and return visit on time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hair density;vellus ratio;single hair follicle accounts for the total hair unit;average hair shaft diameter;Subjective curative effect evaluation of patients;Physician's subjective curative effect evaluation;Quality of life index of dermatosis;Anxiety, depression and stress mixed scale; | — |
Countries
China
Contacts
Public ContactXuegang Xu
Department of Dermatology, The First Hospital of China Medical University
Outcome results
None listed