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A multi-parameter prediction model for pediatric influenza A based on blood routine analysis

A multi-parameter prediction model for pediatric influenza A based on blood routine analysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100760
Enrollment
Unknown
Registered
2025-04-15
Start date
2024-07-01
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

influenza A

Interventions

Influenza group:no
Influenza Like Illness:no

Sponsors

The First Affiliated Hospital of Naval Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 16 Years

Inclusion criteria

Inclusion criteria: Influenza group: clinical manifestations of influenza like diseases, such as fever, headache, muscle pain, and cough; Having positive results in one or more of the following pathogenic tests: positive for influenza A virus nucleic acid test, positive for influenza A virus antigen test, positive for influenza A virus culture and isolation, and a 4-fold or more increase in influenza A virus specific IgG antibody levels in both acute and recovery phase serum samples; Aged 1 to 16 years old; At the first visit, the course of illness was <= 3 days (72 hours). Control group (other children with flu like symptoms): clinical manifestations of flu like diseases such as fever, headache, muscle pain, and cough; During the course of the disease and follow-up examinations, the results of influenza pathogen testing were all negative; Exclude close contact history of influenza; Aged 1 to 16 years old; At the first visit, the course of illness was <= 3 days (72 hours).

Exclusion criteria

Exclusion criteria: Individuals who have already been treated with neuraminidase inhibitors (such as oseltamivir, paramivir, etc.) prior to enrollment; Positive results of pathogenic tests of novel coronavirus and influenza B; Patients with incomplete clinical data;

Design outcomes

Primary

MeasureTime frame
Blood routine;

Secondary

MeasureTime frame
sensitivity;Clinical Decision Curve Analysis;

Countries

China

Contacts

Public ContactLei Lei

The First Affiliated Hospital of Naval Medical University

doctorlei.lei@163.com+86 139 1607 2205

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026