influenza A
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Influenza group: clinical manifestations of influenza like diseases, such as fever, headache, muscle pain, and cough; Having positive results in one or more of the following pathogenic tests: positive for influenza A virus nucleic acid test, positive for influenza A virus antigen test, positive for influenza A virus culture and isolation, and a 4-fold or more increase in influenza A virus specific IgG antibody levels in both acute and recovery phase serum samples; Aged 1 to 16 years old; At the first visit, the course of illness was <= 3 days (72 hours). Control group (other children with flu like symptoms): clinical manifestations of flu like diseases such as fever, headache, muscle pain, and cough; During the course of the disease and follow-up examinations, the results of influenza pathogen testing were all negative; Exclude close contact history of influenza; Aged 1 to 16 years old; At the first visit, the course of illness was <= 3 days (72 hours).
Exclusion criteria
Exclusion criteria: Individuals who have already been treated with neuraminidase inhibitors (such as oseltamivir, paramivir, etc.) prior to enrollment; Positive results of pathogenic tests of novel coronavirus and influenza B; Patients with incomplete clinical data;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine; | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitivity;Clinical Decision Curve Analysis; | — |
Countries
China
Contacts
The First Affiliated Hospital of Naval Medical University