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Effect of perioperative open-lung approach on postoperative pulmonary complications in patients undergoing laparoscopic or robotic surgery: a prospective, randomized controlled trial

Effect of perioperative open-lung approach on postoperative pulmonary complications in patients undergoing laparoscopic or robotic surgery: a prospective, randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100749
Enrollment
Unknown
Registered
2025-04-15
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications

Interventions

STD-O2 group:Intraoperative PEEP fixation + postoperative routine oxygen therapy
OLA-O2 group:Individualized intraoperative PEEP+ postoperative routine oxygen therapy
OLA-HFNC group:Individualized intraoperative PEEP+ postoperative high flow oxygen therapy

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age over 18 years old; 2.ASA class I-III; 3. Scheduled for laparoscopic or robotic abdominal surgery 4. Patients with moderate to high risk of postoperative pulmonary complications according to ARISCAT score; 5. Know and agree to participate in the test and sign a written informed consent.

Exclusion criteria

Exclusion criteria: 1.History of severe lung diseases, such as chronic obstructive pulmonary disease, severe asthma, thoracic and spinal malformations, pleural effusion, pneumothorax and giant bulla, pulmonary surgery and other diseases affecting respiratory compliance 2.Severe cardiac, hepatic, renal, or hematologic disorders; 3.Central nervous system disorders impairing respiratory function; 4.Contraindications for PEEP use: intracranial hypertension, bronchopleural fistula, hypovolemic shock, etc.; 5.Participation in other clinical studies within the last 3 months; 6.Patients who refuse to participate in the trial or cannot cooperate.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Secondary

MeasureTime frame
Pulmonary ultrasound score;Mechanical ventilation parameter;Arterial blood gas;Pain score;Comfort score;

Countries

China

Contacts

Public ContactLijian Chen

The First Affiliated Hospital of Anhui Medical University

chenlijian77@126.com+86 139 6669 9467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026