REM Sleep Behavior Disorder (RBD) is a type of parasomnia characterized by dream enactive behaviors and REM sleep without atonia (RSWA). It is divided into two main categories: idiopathic RBD (iRBD) and secondary RBD. iRBD has no obvious neurological symptoms and signs, but there is a pathological basis of alpha-synucleinopathy,and there is a risk of developing Parkinson's disease, multiple system
Conditions
Interventions
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Meeting the diagnostic criteria for RBD; 2.No gender limitation, with an age is greater than or equal to 18 years old; 3.Having normal comprehension and language expression abilities to communicate with the researchers and being able to complete the questionnaire items successfully.
Exclusion criteria
Exclusion criteria: 1.Suffering from severe somatic diseases, such as those affecting the heart, liver, or kidneys; 2.Having unstable psychiatric disorders; 3.Having a history of alcohol abuse or substance dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of predictors of phenoconversion in patients with RBD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Description of the demographic and clinical characteristics of patients diagnosed with RBD;Assessment of the correlation between electrophysiological indicators and phenoconversion.;Assessment of the correlation between therapeutic interventions, lifestyle, and phenoconversion.;Collection of longitudinal data about the development of RBD and estimation of the conversion time and rate.;Therapeutic intervention efficacy evaluation indicators.;Evaluation of the impact of RBD on daytime function, sleep quality, and cognitive function.;Identification of RBD phenotypes through different biomarkers.; | — |
Countries
China
Contacts
Public ContactYu Huan
Huashan Hospital, Fudan University
Outcome results
None listed