Return of Spontaneous Circulation After Cardiac Arrest
Conditions
Interventions
Intervention Group 1:Mild Hypothermia Therapy: Administer cooling blanket devices, ice caps, and hibernation mixture for targeted temperature management.
CRRT with oXiris Filter: Perform continuous re
Intervention Group 2:Mild Hypothermia Therapy: Administer cooling blanket devices, ice caps, and hibernation mixture for targeted temperature management.
CRRT with ST100 Filter: Perform continuous ren
Control Group:Mild Hypothermia Therapy: Administer cooling blanket devices, ice caps, and hibernation mixture for targeted temperature management.
Sponsors
Nantong Third People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.Patients successfully resuscitated from cardiac arrest; 3.ICU admission duration >=24 hours; 4.Patients meeting clinical indications for CRRT must provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Age <18 years; 2. Severe underlying diseases (e.g., advanced cancer, end-stage renal disease, end-stage liver disease, severe cardiopulmonary dysfunction); 3. Uncontrolled infection or uncontrolled severe infection sources; 4. Severe coagulation dysfunction (e.g., DIC) or intolerance to anticoagulant therapy; 5. Use of other blood purification devices: Prior use of other blood purification devices within 24 hours before enrollment (e.g., other types of CRRT, hemoperfusion); 6. Family refusal to participate; 7. Other study-related exclusion factors: Any additional conditions deemed by the research team to compromise patient safety or study validity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral performance category;ICU mortality rate;ICU mortality rate;ICU expenses; | — |
Secondary
| Measure | Time frame |
|---|---|
| Speed and rate of achieving body temperature standards;Duration of ICU stay; | — |
Countries
China
Contacts
Public ContactWang Yadong
Nantong Third People’s Hospital
Outcome results
None listed