Myopia
Conditions
Interventions
Short-acting observation group:None
Control group:None
Long-term observation group:None
Sponsors
Wenzhou Medical University Eye Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age >=6 years old and =-3.00D, and astigmatism (cylindrical lens) is 0.00 to -1.50D, and anisometric refraction in both eyes =5.0; 6. Intraocular pressure: 10-21mmHg, intraocular pressure difference in both eyes<=5mmHg; 7. No history of ocular organic disease and ocular surgery; 8. Have not used myopia prevention and control methods (such as low-concentration atropine, red light therapy device, orthokeratology lenses, etc.) in the past; 9. No systemic diseases, other endocrine diseases, chromosomal abnormalities and no organic diseases; 10. No previous history of growth hormone therapy; 11. The patient's parent or legal guardian must read, understand and sign the informed consent form, and the patient with reading ability must read (or be read to them by someone else) and sign the informed consent form for the child.
Exclusion criteria
Exclusion criteria: 1. Children with a history of rhGH allergy or systemic diseases, endocrine diseases, or chromosomal abnormalities; 2. Use of drugs such as glucocorticoids that may interfere with the action of growth hormone in the past 3 months; 3. Congenital skeletal abnormalities, lameness or scoliosis; 4. Eye diseases such as glaucoma, cataracts, fundus lesions, active ocular inflammation, etc.; 5. Have strabismus, amblyopia and other eye diseases; 6. History of ocular trauma, ocular surgery, or serious ocular infection; 7. Those who use any myopia prevention and control measures during treatment, such as using low-concentration atropine eye drops or prevention and control lenses or devices; 8. Expected treatment time is less than 12 months and other conditions that the investigator believes are not suitable for inclusion in this clinical trial; 9 Inability to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Axial length;Objective refractive diopter after ciliary muscle paralysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Choroid;Subjective refraction refractive power;Best corrected visual acuity; | — |
Countries
China
Contacts
Public ContactXinjie Mao
Wenzhou Medical University Eye Hospital
Outcome results
None listed