Colorectal cancer
Conditions
Interventions
The Sufentanil group:During induction + surgical suture, 0.1ug/kg sufentanil was given + post-extubation PCIA (Sufentanil)
Analgesic pump: sufentanil 100µg+ Tropisetron 6mg+ sodium chloride injection
The oxycodone group:During induction + surgical suture 0.1mg/kg oxycodone + post-extubation PCIA (Oxycodone)
Analgesic pump: oxycodone 50 mg+ Tropisetron 6mg+ sodium chloride injection 100 ml
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Rated by the American society of anesthesiologists (ASA) as I-III; 2.Type of surgery: laparoscopic radical resection of colorectal cancer; 3.Age 18-70; 4.Gender unlimited; 5.Choose the first surgical operation ; 6.Normal mental health, with certain understanding and communication skills.
Exclusion criteria
Exclusion criteria: 1.History of gastrointestinal disorders (peptic ulcer, Crohn's disease, ulcerative colitis, etc.); 2.Alcohol or opioid abuse, long-term use of opioids ; 3.Allergy or contraindication to sufentanil or oxycodone ; 4.Severe heart/lung/liver/renal insufficiency ; 5.Postoperative infection, bleeding, and mechanical failure of the participant's self-controlled intravenous analgesia device ; 6.Received other trial drugs within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| First postoperative exhaust time;Time of first defecation;Solid food tolerance time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time;Duration of recovery room after anesthesia;Postoperative sedation level;Postoperative incision pain;Postoperative visceral pain;Incidence of adverse reactions;Number of postoperative relief analgesia;Number of analgesic pump compressions in 48 hours after surgery;Patient satisfaction at discharge;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactJiao Hao
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed