Amyotrophic lateral sclerosis
Conditions
Interventions
Amyotrophic lateral sclerosis:None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis based on the revised EL Escorial criteria; 2. 20-75 years old, male or female not limited; 3. Medical history in the past 6 months shows that the disease has progressed; 4. Carrying pathogenic gene mutations; 5. Voluntarily follow and ensure completion of the experimental process; 6. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Merge with clearly defined mental illnesses; 2. Merge with other neurodegenerative diseases or severe systemic diseases; 3. Merge with tumors or other diseases that may reduce survival expectations (such as liver and kidney function, heart failure, severe infection patients) 4. Merge with pregnant patients; 5. Patients are unable to understand the informed consent form and research objectives;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variants in the disease-causing gene for ALS;Disease phenotypic simulation and mechanisms; | — |
Countries
China
Contacts
Public ContactChen Xiangjun
Huashan Hospital, Fudan University
Outcome results
None listed