Non-specific Chronic low back pain
Conditions
Interventions
HD-tACS group:A 30-minute real HD-tACS intervention was applied at a current intensity of 1.5 mA, targeting the left dorsolateral prefrontal cortex, administered 3–5 times per week for a total of 10 s
Sham HD-tACS group:In the sham HD-tACS intervention, electrical stimulation was administered only during the initial 30 seconds and the final 30 seconds of the session.
Sponsors
The Sixth Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years old 2. Low back pain caused by non-specific causes (such as infection, tumor, fracture, arthritis, intervertebral disc herniation, etc.). 3. Right-handed 4. Body mass index range: 18.5-23.9 kg/m^2 5. Chronic non-specific low back pain, pain symptoms lasting more than 3 months, complaining of pain symptoms at least 3 days per week, and pain intensity numerical rating scale (NRS) >=3 6. No contraindications to electroencephalogram examination and tACS
Exclusion criteria
Exclusion criteria: 1. Frequent headache or tinnitus; History of alcohol or drug abuse 2. History of neurological or psychiatric diseases 3. Women are pregnant or breastfeeding 4. Severe scalp trauma, extensive or open head injury, unable to place electrodes 5. Have participated in similar brain stimulation experiments in the past
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting-state endogenous alpha oscillations;Pressure pain threshold;Degree of lumbar dysfunction;Depressive symptoms;State Trait Anxiety;Pain Catastrophizing;Quality of Life; | — |
Countries
China
Contacts
Public ContactYuling Wang
The Sixth Affiliated Hospital, Sun Yat-sen University
Outcome results
None listed