migraine
Conditions
Interventions
invalid group:None
valid group:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-65 years; 2.Patients diagnosed with migraine (without aura and with aura) according to ICHD-3 criteria after a structured outpatient interview and with a migraine duration of 1 year or more; 3.If the patient is already taking migraine prophylactic medication, it needs to be taken at a stable dose for at least 3 months;
Exclusion criteria
Exclusion criteria: 1.Patients with a diagnosis consistent with complications of migraine or migraine-related cyclical disorders; 2.Patients with a history of cluster headaches or hemiplegic migraines; 3.Consecutive migraine headaches (defined as persistent headaches) within 1 month prior to the screening visit; 4.Patients with substance overuse; treatment for alcohol or drug abuse within the previous 12 months, or evidence of alcohol or drug abuse; 5.Patients with major diseases such as malignant tumors; 6.Patients with severe anxiety or depressive disorders and patients with psychotic disorders such as schizophrenia; 7.History of uncontrolled or unstable cardiovascular disease (e.g., ischemic heart disease, coronary vasospasm, or cerebral ischemia), or myocardial infarction, acute coronary syndrome, percutaneous coronary intervention, cardiac surgery, stroke, or transient ischemic attack in the 6 months prior to screening; 8.Patients who are pregnant or breastfeeding; 9.Patients on regular antipsychotic medication in the 3 months prior to enrollment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Is the headache completely pain-free within 2 hours of taking the medication;MBS (the accompanying symptom that bothers patients the most, i.e., nausea, vomiting, photophobia, or phonophobia) disappears 2 hours after the drug is taken; | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache relieved to mild 2 hours after taking medication;No relapse within 24 hours of taking the medication or taking another pain medication; | — |
Countries
China
Contacts
Public ContactGe Tan
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed