Patients who require an indwelling endotracheal tube after oral and maxillofacial surgery
Conditions
Interventions
Dexmedetomidine group (M1 group):Dexmedetomidine nasal drops (1ug/kg )
Dexmedetomidine group (M2 group):Dexmedetomidine nasal drops (1.5ug/kg )
Lidocaine (Group L):Instillation of 2% lidocaine hydrochloride injection through the endotracheal tube
Sponsors
Second Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1: Indwelling nasotracheal tube should be > 24 hours after oral and maxillofacial surgery 2: ASA is graded as Class I or II 3: 30 years <= age <= 70 years
Exclusion criteria
Exclusion criteria: 1: Patients with tracheostomy 2: Patients with severe cardiovascular and cerebrovascular diseases or abnormalities of liver, kidney and other important organs 3: Combined with chronic respiratory diseases, such as chronic obstructive pulmonary disease or bronchial asthma 4: Patients with pre-existing respiratory infections before surgery 5: Those who have allergies to the test drugs and other adverse reactions 6: Patients with cognitive dysfunction before surgery 7: Unwilling to complete the test process or unable to understand the test process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sore throat scored on a 4-point scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency and severity of choking;Wound pain VAS score;Sedation-agitation score ;Postoperative satisfaction evaluation of patients;Hemodynamic parameters (systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate);The number and amount of lidocaine remedy required for each group;Occurrence of delirium within 7 days after operation:; | — |
Countries
China
Contacts
Public ContactFeng Xiao
Second Xiangya Hospital, Central South University
Outcome results
None listed