Connective tissue disease - related interstitial lung disease
Conditions
Interventions
Long-term survival group:NA
Short-term survival group:NA
Sponsors
Gansu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adults aged >= 18 years old, who are diagnosed with CTD-ILD according to the guidelines of the American Thoracic Society/European Respiratory Society (ATS/ERS), have the availability of follow-up, imaging and multi-omics data, and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: Patients with a preliminary diagnosis of idiopathic pulmonary fibrosis (IPF) or other interstitial lung diseases not related to connective tissue diseases, as well as those with severe comorbidities that may interfere with the research results, such as severe cardiovascular diseases, active malignancies, or failure of other major organ systems, and patients with a history of lung transplantation or those who are on the lung transplantation waiting list within the next 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the expression of fibrosis-related proteins;Dynamic changes in systemic metabolites during fibrosis;Dynamic changes of omics characteristics during fibrosis;ROC curve;sensitivity;specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chest CT ;Lung function; | — |
Countries
China
Contacts
Public ContactXiaojun Wang
Gansu Provincial People's Hospital
Outcome results
None listed