colorectal cancer
Conditions
Interventions
Experimental group:ONS supplement with immunonutrients 400kcal while receiving dietary advice
Control group:The control group received dietary advice along with an isocaloric ONS supplement without immunonutrient formulation 400kcal
Sponsors
Lu'an People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1). 18 years old =3 or are not expected to be able to meet the recommended energy intake with oral intake; (4). Subjects with laboratory tests that meet the following criteria: 1) routine blood: haemoglobin >= 80g/L; 2) albumin >= 2.5g/dL; (5). Body mass index (BMI) = 3 months; (8). Those who participate voluntarily and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1). No artificial nutritional support is required; (2). Simultaneous parenteral nutrition; (3). All patients who are not suitable for enteral nutrition, such as gastrointestinal fistula, active bleeding in the gastrointestinal tract, complete intestinal obstruction, severe diarrhoea and other serious digestive and absorption dysfunction; (4). Patients with severe hepatic and renal insufficiency (alanine aminotransferase >=2.5 times the upper limit of normal value; total bilirubin >=1.5 times the upper limit of normal value; creatinine >=1.5 times the upper limit of normal value); (5). Subjects with confirmed diabetes mellitus; (6). Subjects are using fatty milk containing Omega-3 fatty acids, glutamine, glucocorticoids, thyroxine (except for those who have been taking it for more than 3 months), growth hormone, and anti-tumour necrosis factor biologics; (7). Participation in other interventional clinical trials (including drugs, nutritional preparations, medical devices, etc.) within 4 weeks prior to enrolment; (8). Combination of other serious clinical conditions or comorbidities that may jeopardise study conduct and follow-up; (9). Uncontrolled mental illness; (10). Pregnant women, women preparing for pregnancy and their partners, and nursing mothers; (11). Subjects with poor compliance or who, in the opinion of the investigator, are unsuitable for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body mass index (BMI);albumin;lymphocyte count;white cell count;Skeletal muscle content;grip strength;SF-12 Quality of Life Scale;Neutrophil granulocyte count; | — |
Secondary
| Measure | Time frame |
|---|---|
| total protein;haemoglobin;cholesterol;triglyceride; | — |
Countries
China
Contacts
Public ContactXiaoyang Jiang
Lu'an People's Hospital
Outcome results
None listed