Parkinson's disease
Conditions
Interventions
Control group :DBS stimulation is not performed during sleep
High frequency group:DBS stimulation was performed at a frequency of 90 Hz during sleep
Low frequency group:DBS stimulation is performed at a frequency of 4 Hz during sleep
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria: (1) Patients with Parkinson's disease (PD) and treated with deep brain stimulation (DBS) were recruited in West China Hospital of Sichuan University. Junior high school degree or above; (2) Basic computer operation ability; (3) the ability to provide informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclusion Criteria: (1) MMSE score less than 25; (2) comorbid psychiatric disorders or substance use disorders (e.g., severe personality disorders or psychosis) that may affect treatment; (3) Overnight work within 6 weeks prior to the trial or combined with factors or diseases that affect sleep, such as insomnia, severe OSA, etc; (4) Recent suicide attempt or active suicidal ideation; (5) Severe cardiopulmonary diseases, liver and kidney diseases, etc; (6) Patients who are unable to cooperate with the completion of memory tasks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of memory tasks;Accuracy of memory tasks; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination Score;Hamilton Anxiety Rating Scale (HAM-A) score;Hamilton Depression Rating Scale (HAM-A) score;Pittsburgh Sleep Quality Index;Epworth Sleepiness Scale score; | — |
Countries
China
Contacts
Public ContactSenlin Yin
West China Hospital, Sichuan University.
Outcome results
None listed