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The intervention effect of Qili Qiangxin Capsules on pulmonary arterial hypertension

The effect and mechanism of Qili Qiangxin Capsules on pulmonary hypertension caused by left heart disease

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100579
Enrollment
Unknown
Registered
2025-04-11
Start date
2025-04-16
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary hypertension caused by left heart disease

Interventions

Conventional medication group:Guidelines recommend standardized drugs for the treatment of heart failure
combined Qiliqiangxin capsule group:combined Qiliqiangxin capsule

Sponsors

Liaocheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age over 18 years old, pulmonary artery systolic pressure >= 40mmHg measured by echocardiography (2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension), clinical diagnosis of heart failure with preserved or reduced ejection fraction (AHA/ACC/HFSA Heart Failure Management Guidelines 2022); 2.Age over 18 years old, pulmonary artery systolic pressure = 40mmHg measured by echocardiography (2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension), clinical diagnosis of heart failure with preserved or reduced ejection fraction (AHA/ACC/HFSA Heart Failure Management Guidelines 2022);

Exclusion criteria

Exclusion criteria: 1.Other types of pulmonary hypertension or targeted drugs for oral lowering of pulmonary arterial hypertension;combined with acute inflammatory response; 2.Concomitant acute inflammatory disease; 3.severe liver and kidney dysfunction; 4.Merge malignant tumors or Immunodeficiency diseases;

Design outcomes

Primary

MeasureTime frame
Pulmonary artery systolic pressure;

Secondary

MeasureTime frame
HMGB1;CXCL14;6 minutes walk test;NT-proBNP;WHO classification;

Countries

China

Contacts

Public ContactMing-ting Liang

Liaocheng People's Hospital

lmting007@163.com+86 635 827 6837

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026