Asthma
Conditions
Interventions
Accelerated group:An accelerated dose increase was performed with NHD
Conventional group:Use NHD for regular dose escalation as per product instructions
Sponsors
Foshan Women and Children Hospital
Eligibility
Sex/Gender
All
Age
5 Years to 14 Years
Inclusion criteria
Inclusion criteria: (1) Age 5-14 years old; (2) IgE mediated mild to moderate allergic asthma with or without allergic rhinitis caused by dust mite allergens (house dust mites and or dust mites) : a. Children with mild to moderate allergic asthma and well-controlled levels (refer to the diagnostic criteria of the Standardized Diagnosis and Treatment Recommendations for Bronchial Asthma in Children 2020 Edition); b. Skin prick test for house dust mite and or dust mite wind mass>=++ (skin index =0.5) or house dust mite and or dust mite sIgE>=0.7 kU/L;
Exclusion criteria
Exclusion criteria: 1. In the judgment of the investigator, the subject and/or parent/legal guardian are unable to understand and comply with the requirements of the study; 2. Patients with severe or uncontrolled asthma (FEV1 <70% predicted value) and irreversible airflow obstruction; 3. Patients on beta-blockers or Angiotensin-converting enzyme (ACE) inhibitors; 4. Severe autoimmune diseases, including AIDS, inflammatory bowel disease and other immune deficiency diseases and autoimmune diseases, severe psychological disorders,cancer. 5.Poor compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tolerability;Changes in laboratory test values (hematology, clinical chemistry, and urinalysis);Lung function;ACT/C-ACT;Visual analogue scale score, VAS; | — |
Countries
China
Contacts
Public ContactJun Bai
Foshan Women and Children Hospita
Outcome results
None listed