Adverse reactions, hypotension, decreased oxygen saturation and so on were observed by gastroscopy.
Conditions
Interventions
Group A:Patients in group A were given rapid intravenous induction with esketamine(0.3mg/kg)and propofol(2mg/kg).
Group B:Patients in group A were given rapid intravenous induction with esketamine(0.5mg/kg)and propofol(2mg/kg).
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. the age was 20-45 years old; 2. all races were acceptable; 3. patients needed painless gastroenteroscopy; 4. ASA grade 1-2; 5. patients signed written consent for anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients have serious underlying diseases, such as poorly controlled hypertension, severe ischemic heart disease, congestive heart failure and poor liver and kidney function, kidney disease requiring dialysis, and so on. 2. The patient did not sign the consent form for anesthesia. 3. Those who are allergic to esmolamine or excipients. 4. Patients with severe risk of hypertension or elevated intracranial pressure. 5. patients with severe mental disorders. 6. Patients with hyperthyroidism who are untreated or with poor therapeutic effect. 7. Patients with high intraocular pressure, such as glaucoma. 8. There are patients with drug abuse or dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total consumption of propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;Induction time?Operation time;Awakening time;MOAA/S one minute after administration;Adverse reaction;Additional amount of propofol is required;Endoscopic physician / anesthesiologist / patient satisfaction; | — |
Countries
China
Contacts
Public ContactJia Han
Deyang People's Hospital
Outcome results
None listed