Bronchiectasis
Conditions
Interventions
Physiological saline group:The subjects nebulized 18F NaF and underwent PET/CT scanning after nebulization. Each subject underwent EIT examination to determine pulmonary obstructive and compliance.
Compound Ipratropium Bromide Solution for Inhalation+ Saline Group:The subjects first nebulized and inhaled carbidone, then nebulized and inhaled 18F NaF, and after nebulization was completed, PET/CT
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
14 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients included in the study must meet all three criteria (1. 2. 3.) and be evaluated by experienced clinical doctors. 1 Age range: 18-75 years old; 2 In terms of imaging, high-resolution CT shows the following direct signs: "signet ring sign" is usually accompanied by bronchial wall thickening, and the ratio of bronchial/concomitant pulmonary artery diameter (B/A>1); From the center to the periphery, the bronchi do not gradually become thinner; Dilated bronchial shadow can be seen within 1 cm from the pleura. Indirect signs: thickening of bronchial wall; Mucous impaction; Mosaic sign or "gas trap" was found on expiratory CT scan; 3 Symptomatically, there are clinical manifestations of chronic cough, purulent sputum, and/or recurrent hemoptysis.
Exclusion criteria
Exclusion criteria: 1 Cannot tolerate salt water atomization; 2 Cannot tolerate lung function tests or pulmonary ventilation imaging examinations; 3 Those who cannot understand the experimental operation process and correctly use experimental instruments; 4 Women who are preparing for pregnancy, pregnant, or breastfeeding; 5 Merge severe systemic diseases and mental abnormalities; Merge malignant tumors, etc 6 Refuse to participate in the experiment.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Obstructive pulmonary disease; | — |
Primary
| Measure | Time frame |
|---|---|
| Total lung uptake value;Total camera value of branch expansion area;Lung compliance; | — |
Countries
China
Contacts
Public Contactlin-ling cheng
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed