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Study on the effect and mechanism of non-invasive spinal cord electrical stimulation based on temporally interfering in promotingnerve function recovery after spinal cord injury

Study on the effect and mechanism of non-invasive spinal cord electrical stimulation based on temporally interfering in promotingnerve function recovery after spinal cord injury

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100524
Enrollment
Unknown
Registered
2025-04-10
Start date
2024-11-01
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury, neuropathic pain after spinal cord injury, defecation disorder

Interventions

TI group:non-invasive spinal cord electrical stimulation based on temporally interfering
Control group:None

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The degree of spinal cord injury meets the international standard of SCI neurological classification established by the American Spinal Cord Injury Association to determine the degree of injury as: Grade B, C or D or neuropathic pain after spinal cord injury or neurogenic bladder after spinal cord injury; (2) Onset 1 month to 3 years; (3) The end of previous surgery or medical treatment, the condition is stable; (4) can cooperate with time domain interference non-invasive spinal cord electrical stimulation treatment, and good cognition; (5) Age 18-80 years old; (6) Consent and sign the informed consent for treatment. 2. Onset 1 month to 3 years; 3. The end of previous surgery or medical treatment, the condition is stable; 4. It can cooperate with time-domain interference non-invasive spinal cord electrical stimulation treatment, and the cognitive function is good; 5. Age 18-80 years old; 6. Consent and sign the informed consent for treatment;

Exclusion criteria

Exclusion criteria: 1. Vital signs are not stable; 2. Skin damage in severely infected and irritated areas; 3. There are contraindications of electrical stimulation; 4. The treatment compliance was poor, and the treatment could not be carried out according to the study design;

Design outcomes

Secondary

MeasureTime frame
Timed Up and Go Test (TU-GT);6-Minute Walking Test (6-MWT);Barthel Index (BI);short-form of McGill pain questionnaire(SF-MPQ);lower urinary tract symptom score(LUTS);

Primary

MeasureTime frame
Graded redefined assessment of strength, sensibility and prehension(GRASSP);Fugl-Meyer upper extremity score (UEFM)?Fugl-Meyer assessment lower extremity score (LEFM);American Spinal Injury Association Impairment Scale (AIS);Berg Balance Scale (BBS);

Countries

China

Contacts

Public ContactCheng Ruidong

Zhejiang Provincial People's Hospital

474429740@qq.com+86 150 6884 6908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026