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A retrospective study on the craniofacial characteristics of patients with hemifacial microsomia based on a multicenter, large-sample case series

A retrospective study on the craniofacial characteristics of patients with hemifacial microsomia based on a multicenter, large-sample case series

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100509
Enrollment
Unknown
Registered
2025-04-10
Start date
2024-10-01
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemifacial Microsomia

Interventions

Hemifacial Microsomia group:None

Sponsors

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 30 Years

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with hemifacial microsomia through 3D CT scans at the outpatient clinics of the participating centers of this project from January 2008 to August 2024. Diagnostic criteria: Criterion (1) is mandatory, and at least one of criteria (2) and (3) must be met. (1) Characteristic mandibular hypoplasia (2) Associated ear anomalies, including microtia, preauricular tags, preauricular pits, external auditory canal anomalies, conductive hearing loss, or middle ear anomalies (3) Presence of indirectly related anomalies, such as soft tissue hypoplasia on the affected side, midface anomalies, ocular abnormalities, spinal or other skeletal anomalies, or other systemic malformations 2. Age range of cases: From birth to 30 years old (inclusive). 3. Confirmation via 3D CT that the patient has not undergone any maxillofacial surgical treatments such as distraction osteogenesis, orthognathic surgery, or bone graftin

Exclusion criteria

Exclusion criteria: 1. Patients with concurrent maxillofacial trauma, tumors, or other diseases affecting the skeletal structure. 2. Patients with other associated syndromes. 3. Poor-quality 3D CT images that make it difficult to identify bony landmarks.

Design outcomes

Primary

MeasureTime frame
Occlusal plane deviation;Ratio of mandibular ramus height;

Secondary

MeasureTime frame
Other mandibular/maxillary bone indices;Orbital volume ratio; Measurement indices of the temporal bone, zygomatic bone, and others.;

Countries

China

Contacts

Public ContactGang Chai

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University

139188218178@163.com+86 139 1821 8178

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026