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Alpha-frequency transcranial alternating current stimulation modulates experimental pain in healthy subjects: a randomized controlled clinical trial

Alpha-frequency transcranial alternating current stimulation modulates experimental pain in healthy subjects: a randomized controlled clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100508
Enrollment
Unknown
Registered
2025-04-10
Start date
2025-01-11
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain

Interventions

shame a-tACS:shame a-tACS
active a-tACS:active a-tACS

Sponsors

Zhujiang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Voluntarily cooperate with the study and sign the informed consent form; Healthy people aged 18-30 years; Right-handedness as assessed by the Edinburgh Hands Scale.

Exclusion criteria

Exclusion criteria: Diagnosed with psychiatric illness, central nervous system disease currently or within the past 5 years and is receiving treatment; Has a history of acute or chronic pain, or is currently experiencing any form of pain; Regularly taking any psychotropic, sleep, or pain-relieving medications; Uncontrolled hypertension, heart failure, or acute myocardial infarction; cognitive impairment (score < 26 points on MoCA examination); Previous invasive electrical or magnetic brain stimulation, intracranial metal implantation.

Design outcomes

Primary

MeasureTime frame
Subjective perceived pain score;

Secondary

MeasureTime frame
Beta values of activation in brain regions ;FC values;PSD;LEP(N2-P2);

Countries

China

Contacts

Public ContactWu Wen

Zhujiang Hospital, Southern Medical University

wuwen66@163.com+86 136 1142 7189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026