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Clinical study on preventing gastric insufflation and reflux and aspiration during the induction of general anesthesia in obese patients based on THRIVE and PCV-VGIRV

Clinical study on preventing gastric insufflation and reflux and aspiration during the induction of general anesthesia in obese patients based on THRIVE and PCV-VGIRV

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100499
Enrollment
Unknown
Registered
2025-04-10
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

H:THRIVE pre-absorbing oxygen for 5 minutes, oxygen flow rate of 30L/min, FiO2 100%. During anesthesia induction, the oxygen flow rate was increased to 50L/min, and FiO2 was 100%. The anesthesia induc
I:Conventional masks pre-absorb oxygen for 5 minutes, oxygen flow rate of 6L/min, FiO2 100%. Anesthesia-induced drugs were in the same group C. After the patients eyelash reflex disappears, the same a
C:Conventional masks pre-absorb oxygen for 5 minutes, oxygen flow rate of 6L/min, FiO2 100%. Drugs for inducing general anesthesia: midazolam 0.05 mg/kg, sufentanyl 0.5 µg/kg, propofol 2 mg/kg and roc

Sponsors

Second Affiliated Hospital of Jiaxing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: This topic evaluates the clinical effect of THRIVE and PCV-VGIRV in preventing gastric intake and reflux and aspiration during the induction of general anesthesia in obese patients, providing new ventilation strategies for obese patients and improving the safety of anesthesia surgery.

Exclusion criteria

Exclusion criteria: This topic evaluates the clinical effect of THRIVE and PCV-VGIRV in preventing gastric intake and reflux and aspiration during the induction of general anesthesia in obese patients, providing new ventilation strategies for obese patients and improving the safety of anesthesia surgery.

Design outcomes

Primary

MeasureTime frame
Gastric insufflation rate under ultrasound;CSA cannulation-CSA basics;Reflux rate;Micro-absorbing rate;Gastric insufflation grading under direct laparoscopic vision;

Countries

China

Contacts

Public ContactShuai Kang

Second Affiliated Hospital of Jiaxing University

15024340122@163.com+86 150 2434 0122

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026