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Exploration of Optimizing the Therapeutic Effect of Mechanical Thrombectomy for Ischemic Stroke Based on Remote Ischemic Conditioning (RIC) Technology

Exploration of Optimizing the Therapeutic Effect of Mechanical Thrombectomy for Ischemic Stroke Based on Remote Ischemic Conditioning (RIC) Technology

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100489
Enrollment
Unknown
Registered
2025-04-10
Start date
2025-04-17
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral arterial thrombosis

Interventions

experimental group:A RIC is performed by pressurizing the unaffected upper arm to a blood pressure threshold of 200mmHg using an automated specialized treatment device/conventional mercury sphygmomano
Control group:None

Sponsors

The Third People's Hospital of Chengdu City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Diagnosed with IS according to the "China Acute Ischemic Stroke Diagnosis and Treatment Guidelines 2018"; 3. Within 24 hours of onset; 4. National Institute of Health Stroke Scale (NIHSS) score National Institute of Health Stroke Scale (NIHSS) score >=6 points; 5.Computed tomography (CTA) of the head for consideration of large artery occlusion; 6. Patients with acute IS who have anterior circulation with onset time of 6-24 hours for large vessel occlusion.Patients with acute IS with large-vessel occlusion should meet the DAWN study enrollment criteria.

Exclusion criteria

Exclusion criteria: 1. Prior severe disability [modified Rankin Scale (mRS) score >= 3]; 2. The presence of distal ischemia management treatment contraindications, such as the presence of more serious soft tissue injury, fracture or vascular injury of the compression limb; limb acute or subacute stage venous thrombosis, subclavian artery blood theft syndrome, and so on; 3.Patients who refuse to participate in the program or have poor compliance.

Design outcomes

Primary

MeasureTime frame
Assessment of neurological deficits;Status of revascularization;

Secondary

MeasureTime frame
Ancillary findings;Complications;

Countries

China

Contacts

Public ContactLiu Hua

The Third People's Hospital of Chengdu City

45358307@qq.com+86 180 1135 1793

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026