Acute hypoxic respiratory failure and hypercapnia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients with acute hypoxic respiratory failure and hypercapnia; (2) Adult patients (>=18 years), regardless of gender; (3) PaO2/FiO2 50mmHg; (4) Patients who agree to participate in this trial and sign the "Informed Consent Form of Subjects".
Exclusion criteria
Exclusion criteria: (1) Contraindications for esophageal catheter insertion: Gastric ulcer, esophageal varices, pharyngeal or laryngeal tumors, etc.; (2) In special circumstances, immediate tracheal intubation is required; (3) NIV contraindications or intolerance; (4) Pregnant women; (5) Refusal to sign the informed consent form; (6) Patients considered unsuitable by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory drive; | — |
Countries
China
Contacts
West China Hospital of Sichuan University