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The effectiveness of platelet-rich plasma combined with pulsed radiofrequency in the treatment of sciatic nerve injury

The effectiveness of platelet-rich plasma combined with pulsed radiofrequency in the treatment of sciatic nerve injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100468
Enrollment
Unknown
Registered
2025-04-10
Start date
2025-04-10
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sciatic nerve injury

Interventions

Experimental group1:Pulsed radiofrequency combined with rehabilitation
Experimental group 2:Platelet-rich plasma combined with rehabilitation
Experimental group 3:Platelet-rich plasma combined with rehabilitation and pulsed radiofrequency
Control group:Rehabilitation treatment

Sponsors

General Hospital of the Western Theater of the Chinese People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. meet neurological diagnostic criteria for peripheral nerve injury; 2. patients with sciatic nerve injuries that do not require surgical intervention; 3. the site of injury is the mid to posterior thigh of the lower limb; 4. male patients in the age group of 18-60 years old; 5. the duration of the disease was 3 weeks or more after the injury; 6. no treatment related to the promotion of nerve repair was received in the 2 weeks before the intervention of this study, if the patient's pain is obvious, acetaminophen tablets (500mg, ?4/day) can be given; 7. Patients understand the main contents and risks of this study, participate voluntarily and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. patients who could not fulfil the inclusion criteria; 2. patients who cannot meet the criteria for platelet-rich plasma collection; 3. Patients who cannot guarantee that they can complete treatment and follow-up on time; 4. Patients with severe cardiopulmonary disorders, blood disorders, skin disorders, infections, psychological disorders, or electrode implants in the body.

Design outcomes

Primary

MeasureTime frame
Motor and sensory function recovery rating after peripheral nerve injury;

Secondary

MeasureTime frame
Pain;Electrophysiological study change;Musculoskeletal ultrasound indicators;

Countries

China

Contacts

Public ContactCongmin Yang

General Hospital of the Western Theater of the Chinese People's Liberation Army

471838911@qq.com+86 152 0827 8139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026