Skip to content

The clinical efficacy study of acupuncture based on the brain-gut axis in regulating the vagus nerve for patients with functional constipation and depression.

The clinical efficacy study of acupuncture based on the brain-gut axis in regulating the vagus nerve for patients with functional constipation and depression.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100467
Enrollment
Unknown
Registered
2025-04-10
Start date
2025-04-17
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

constipation and depression

Interventions

Group A:Electroacupuncture stimulation at bilateral Zusanli (ST36), Shousanli (LI10), Tian Shu (ST25), and Neiguan (PC6) points.

Sponsors

The First People’s Hospital of Zhangjiagang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for functional constipation with depression. 2. Patients with onset age between 20~60 years old. 3. The individual agrees to accept and insist on completing the treatment, cooperates with the study, accepts the telephone and outpatient follow-up process, and signs the informed consent form. 4. There is no current use of medication for diseases related to this study, or the time between the last treatment of constipation or depression and the treatment of this study is more than 1 month.

Exclusion criteria

Exclusion criteria: 1. Those with a history of abdominal or rectal and anal surgery. 2. Irritable bowel syndrome and organic or drug-induced constipation; Secondary to endocrine, metabolic, or neuropathic constipation. 3. Patients with heart, liver, kidney damage or cognitive dysfunction, aphasia, or unable to cooperate with sample collection and treatment. 4. Those who are pregnant, lactating and have a pregnancy plan in the past three months. 5. Patients with coagulation dysfunction or those who have been using anticoagulants such as warfarin and heparin.

Design outcomes

Primary

MeasureTime frame
Self-initiated bowel movements;

Secondary

MeasureTime frame
Depressive condition;Stool characteristics;Heart rate variability;Cortisol;Adrenocorticotropic hormone;

Countries

China

Contacts

Public ContactGe Lingling

The First People’s Hospital of Zhangjiagang City

834140112@qq.com+86 188 6263 7831

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026