Chronic constipation
Conditions
Interventions
Intervention Group:Swallow vibrating capsules, one capsule at a time, 2 times/week, for 4 weeks.
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years old; 2. Meet the diagnostic criteria for chronic constipation; 3. There are no obvious organic lesions in colonoscopy in hospitals above the second level within 3 years; 4. Willing to participate in this study and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Trying to conceive, pregnant or lactating; 2. Allergy to polymer materials; 3. Users of permanent pacemakers (e.g. implantable cardioverter-defibrillators) or any electronic/magnetic/mechanical control devices; 4. Dysphagia, gastric outlet obstruction, intestinal organic lesions (obstruction, stenosis, bleeding, inflammation or cancer, etc.); 5. Intestinal polyps or gastrointestinal ESD surgery within the past 3 months; 6. "alarm" symptoms in recent years, including abnormal weight loss (more than 10% in the last three months); 7. Have serious heart, lung, kidney and other systemic diseases; 8. Those who have been given oral drugs that are prohibited in this study in the past 2 weeks (such as gastrointestinal prokinetic drugs, intestinal emollients, antidepressants, drugs for the treatment of Parkinson's disease, opioids and other anesthetics, aluminum magnesium hydroxide, etc.); 9. Severe depression, anxiety and other mental illnesses that cannot cooperate with the completion of the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart Rate Variability; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events;Defecation frequency; | — |
Countries
China
Contacts
Public ContactHou Xiaohua
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed