None
Conditions
Interventions
Experimental group:Patients received a slow bolus of sufentanil 0.2-0.4 µg/kg intravenously, and at the same time continued intravenous infusion of remimazolam besylate through intravenous administrat
Control group:The patient received a slow bolus of sufentanil 0.2-0.4 µg/kg intravenously, and at the same time continued intravenous infusion of propofol with a total amount of 1.5-2mg/kg for <=3 min
Sponsors
People's Hospital of Leshan
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.18 years <= age <=80 years; 2.ASA Grade I - III; 3.18 kg/m^2 <=BMI <=28 kg/m^2; 4.Patients undergoing transurethral prostate surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1.Preoperative assessment of patients with difficult airway; 2.Patients who have contraindicated general anesthesia or plan to combine other anesthesia methods; 3.Patients with severe craniocerebral injury or major respiratory and circulatory organ dysfunction; 4.Patients with neuromuscular disease, mental illness or long-term use of benzodiazepines; 5.Patients with auditory or visual dysfunction or other conditions affecting normal communication; 6.Patients with a known allergy to any of the drugs involved in the study; 7.Patients who refused to participate in the study or did not cooperate with the study and who were determined by the investigator to be unfit to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of agitation in patients with PACU (RASS score >=3); | — |
Secondary
| Measure | Time frame |
|---|---|
| Study how long it takes to follow verbal commands after withdrawal;The time from drug withdrawal to laryngeal mask removal was studied;The time from the end of drug administration until subjects met the PACU criteria (the PACU criteria was the modified Aldrete score ?9 points);;Incidence of resedation after laryngeal mask removal (RASS score decreased by at least 1 point immediately compared to laryngeal mask removal); | — |
Countries
China
Contacts
Public ContactLiang Jin
People's Hospital of Leshan
Outcome results
None listed