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To observe the characteristics of neurodegenerative changes in patients with ocular and systemic diseases by confocal laser scanning microscopy and optical coherence tomography angiography.

To observe the characteristics of neurodegenerative changes in patients with ocular and systemic diseases by confocal laser scanning microscopy and optical coherence tomography angiography.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100421
Enrollment
Unknown
Registered
2025-04-09
Start date
2022-07-28
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes,Parkinson’s disease

Interventions

Observation group:None

Sponsors

The First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age = 16 years old, = 80 years old in our department diagnosed with dry eye, glaucoma, keratoconus, diabetic retinopathy and other eye diseases and Alzheimer 's disease, Parkinson 's disease, stroke and other systemic diseases in patients.

Exclusion criteria

Exclusion criteria: ( 1 ) The patient was 80 years old. ( 2 ) Patients with a history of ocular trauma ; ( 3 ) patients with ocular physical and chemical damage ; ( 4 ) Patients with ocular genetic diseases

Design outcomes

Primary

MeasureTime frame
Density of corneal nerve;Length of corneal nerve;—

Countries

China

Contacts

Public ContactHong Zhang

The First Affiliated Hospital of Harbin Medical University

435694215@qq.com+86 451 8555 3951

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026