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Research on the migration effect and mechanism of working memory training in improving anhedonia

The effects of working memory training on anhedonia in schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100418
Enrollment
Unknown
Registered
2025-04-09
Start date
2025-04-15
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Working memory training group:Working memory training + treatment as usual. The training group used the dual n back task in addition to the business-as-usual treatment for working memory training , du
Control group:Treatment as usual, consistent with cohort training group, post-test completed five days after the pre-test.

Sponsors

Institute of Psychology, Chinese Academy of Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosis was consistent with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) (APA, 2013) for the diagnosis of schizophrenia; 2.Age 18-65 years old; 3.Literacy level of junior high school and above; 4.Subjects are willing to participate and cooperate in completing the test.

Exclusion criteria

Exclusion criteria: 1.Co-morbid conditions with other mental illnesses (e.g., anxiety disorders, obsessive-compulsive disorder, etc.); 2.IQ below 70; 3.History of drug addiction or substance abuse; 4.History of traumatic brain injury or neurological disorders; 5.Non-right-handedness; 6.MECT treatment within the past 8 weeks; 7.Change of medication within 2 weeks; 8.Unfit to participate in a brain imaging scan due to metal in the body, claustrophobia, pregnancy, etc.

Design outcomes

Primary

MeasureTime frame
Working memory capability;Anhedonia;

Secondary

MeasureTime frame
Neural Functional;Clinical Symptom;Reward Function;

Countries

China

Contacts

Public ContactRaymond C. K. Chan

Institute of Psychology, Chinese Academy of Sciences

rckchan@psych.ac.cn+86 136 5130 5662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026