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Oxalidine prevents sufentanil-induced cough during general anesthesia induction: A randomized controlled trial

Oxalidine prevents sufentanil-induced cough during general anesthesia induction: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100414
Enrollment
Unknown
Registered
2025-04-09
Start date
2025-04-11
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraperitoneal lesions

Interventions

Group OS:2mg oxelidine is configured to 5ml
Group SS:0.9% saline 5ml

Sponsors

The First People's Hospital of Tianshui
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: The patients were ASA1-3 grade patients aged 18-70 years who required sufentanil induction under general anesthesia.

Exclusion criteria

Exclusion criteria: Patients with allergies, sinus bradycardia, severe neurological, respiratory, or cardiovascular disease, narcotic drug dependence and recent opioid use, liver and kidney dysfunction, pregnancy, lactation, and delivery surgery, and upper respiratory infections within 2 weeks that may cause spontaneous cough.

Design outcomes

Primary

MeasureTime frame
Incidence of choking;

Secondary

MeasureTime frame
Number of patients with different degree of cough ;Systolic blood pressure, diastolic blood pressure, heart rate and oxygen saturation;

Countries

China

Contacts

Public ContactLi Chenguang

The First People's Hospital of Tianshui

lichguang227@163.com+86 187 9418 9553

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026