Gastric cancer/atelectasis
Conditions
Interventions
Titration group:In the FiO2 titration group, inhalation oxygen concentration was set at 100% mask for 3min before intubation, manual reexpansion was performed after intubation, respiratory parameters
If SpO2 < 97%, FiO2 is increased by 0.1, and SpO2 is evaluated again 2 minutes later. Intraoperative titration of inhaled oxygen concentration was used to maintain, and after extubation, the patient w
Control group:Control group: Before intubation, patients were given 100% oxygen inhalation concentration mask ventilation for 3min, manual reexpansion was performed after intubation, respiratory param
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged >=65 years and undergoing radical gastrectomy; 2. BMI 18.5 ~ 25kg/m^2; 3. ASA Grade II or III; 4. There was no obvious abnormality in lung function; 5. No spine or thoracic deformity, no difficult airway, asthma or COPD; 6. Estimated operation time >=2h; 7. Volunteer and sign the informed consent
Exclusion criteria
Exclusion criteria: 1. Preoperative hypertension was not effectively controlled or poorly controlled (systolic blood pressure >=180mmHg or diastolic blood pressure >=110mmHg); 2. severe respiratory complications (including but not limited to chronic obstructive pulmonary disease, asthma, lung cancer, tuberculosis, etc.); 3. Severe damage to liver and kidney function; Serious cardiovascular system diseases: such as severe arrhythmia, heart failure, acute coronary syndrome and other underlying diseases; 4. Participate in other clinical studies within the last 3 months; 5. Situations in which other researchers consider it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of postoperative atelectasis;Incidence of hypoxemia;Pulmonary function test, clinical pulmonary infection score, postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| General vital signs, blood gas analysis parameters;The incidence of surgical incision infection, mortality during hospitalization, etc; | — |
Countries
China
Contacts
Public ContactLi Yun
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed