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Comparison of analgesic effect of wound injection of ropivacaine and intravenous injection of dexamethasone in children after tonsillectomy and analysis of risk factors of postoperative fever

Comparison of analgesic effect of wound injection of ropivacaine and intravenous injection of dexamethasone in children after tonsillectomy and analysis of risk factors of postoperative fever - Comparison of analgesic effect between ropivacaine and dexamethasone

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100405
Enrollment
Unknown
Registered
2025-04-09
Start date
2024-08-22
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic tonsillitis

Interventions

A:Tonsillectomy was performed on all patients after a unified anesthesia program. The operation was performed by an experienced otolaryngology attending physician. There was no difference in the mode
B:Patients in group B were given 10mg dexamethasone intravenously once a day after returning to the ward until discharge.
C:Patients in group C were injected with ropivacaine after the operation according to the method of group A, and were given 10mg dexamethasone intravenously once a day after resuscitation to the ward
D:Patients in group D were injected with dexamethasone submucous membrane of bilateral tonsil fossa and underwent infiltration anesthesia. All patients returned to the ward after anesthesia recovery.

Sponsors

Foshan Sanshui District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 14 Years

Inclusion criteria

Inclusion criteria: 1) In line with the indications of tonsillectomy, not combined with adenoidectomy; 2) Aged 3-14 years old; 3) The ASA classification of anesthesia was grade I-II, excluding diseases of the central nervous system, respiratory system, circulatory system and endocrine system. 4) No liver and kidney dysfunction, abnormal coagulation function, and no history of anesthesia surgery.

Exclusion criteria

Exclusion criteria: 1) Control of acute tonsil inflammation for less than 3 weeks; 2) Patients who have received any analgesic drugs in the last 24 hours before surgery; 3) Hemorrhagic disease or any serious systemic disease; 4) Patients with other diseases affecting pharyngeal pain, such as excessively long styloid process; 5) Asymmetric enlargement of tonsil, postoperative pathological examination indicated malignancy; 6) People who are known to be allergic to local anesthetics.

Design outcomes

Primary

MeasureTime frame
visual analogue scale,VAS;

Secondary

MeasureTime frame
White blood cell counts;neutrophil counts ;

Countries

China

Contacts

Public ContactHuang Jia

Foshan Sanshui District People's Hospital

hj1990@126.com+86 135 3313 9885

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026